产品货号：
Z38537
中文名称：
GPX1抗体
英文名称：
Anti-GPX1 Antibody (Clone#8B10)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GPX1 Antibody (Clone#8B10) |
| 指标别名 | glutathione peroxidase 1;GPx 1;GPX1;GSHPx 1;GSHPX1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | GPX1 |
| 克隆号 | 8B10 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human GPX1 (116-146aa EVNGAGAHPLFAFLREALPAPSDDATALMTD),different from the related mouse sequence by six amino acids and from the related rat sequence by five amino acids. |
| 实际分子量 | 22KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Glutathione peroxidase 1,also known as,GPX-1 is an enzyme that in humans is encoded by the GPX1 gene.It is mapped to 3p21.31.This gene encodes a member of the glutathione peroxidase family,consisting of eight known glutathione peroxidases (Gpx1-8) in humans.Glutathione peroxidase functions in the detoxification of hydrogen peroxide,and is one of the most important antioxidant enzymes in humans.It has been reported that the protein encoded by this gene protects from CD95-induced apoptosis in cultured breast cancer cells and inhibits 5-lipoxygenase in blood cells,and its overexpression delays endothelial cell growth and increases resistance to toxic challenges.GPX1 is one of only a few proteins known in higher vertebrates to contain selenocysteine,which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA. |
| Uniprot ID | P07203 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry(Paraffin-embedded Section) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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